Name: Faculty Achievement
Date: 2022-12-05
Venue: Metro College of Health Sciences & Research
Description:
Dr. Kanak Lata (Director-Education), Dr. Praveen Kumar Gaur (Principal) & Dr. Niharika (Associate Professor) Metro College of Health Sciences and Research (Pharmacy), published paper on the topic “CURRENT NOVEL NANOCARRIERS IN DRUG DELIVERY: A REVIEW” in an International journal entitled “Hacettepe University Journal of the Faculty of Pharmacy”. This journal is indexed in Scopus and also in several national scientific journal lists. The journal aims to provide a cross-disciplinary and international forum for researchers to disseminate innovative research in the pharmaceutical, life, health, and cosmetic sciences.
In this article, the authors has emphasized on variety of nanocarriers, used for drug delivery applications, especially in Targeted sites.Nanotechnology’s applicability in medicine, specifically drug delivery, is expected to grow substantially. Because of their ability to overcome drug transportation constraints, nanotechnology in drug transport systems could be a possible technique for overcoming traditional drug delivery. A targeted Drug Delivery system can enhance the transport and nearby awareness of drugs. Targeted transport processes for most cancer therapeutics have proven a steep upward push over the beyond few decades. However, in comparison to the plethora of hit pre-scientific studies, the best passively centered Nanocarriers (NCs) had been accredited for scientific use and none of the actively centered NCs have superior beyond scientific trials.
The review compiled the understanding of the utilization of nanocarriers, that have been used to circumvent the problems associated with conventional as well as antitumor/ neurological drug delivery systems, including their non specificity, severe side effects, burst release and damaging the normal cells.
Nanomedicines are capable drug delivery systems which could yield progression in therapeutic efficacy. They have numerous figures of advantages over conventional DDS that be afflicted by the sudden release of the drugs. The encapsulation of the drug into nanocarriers can stable a drug from environmental and biological degradation, lowering drug dosing and accelerating healing process via controlling drug release. They could enhance solubility of drugs, permeability, and bioavailability which might be commonly difficult to target the diseased site. The distinguished properties of Nanoparticles, like, flexible synthesis, controlled size, Optimal drug release, biocompatibility and response to environmental surroundings of cancerous cells have been acknowledged and it has been used in an intensive form ofapplications. Numerous advancements have been progressing with time in the modification of surface attributes of nanocarriers to perform unique binding with ligand and releasing drugs at the target site. Enhancement of those techniques mixed with the vast development made within side the subject of Nanocarriers as an advanced comprehension. The apparent improvement in commercial products shows significant results In vivo, predicting the efficacy and safety of nanocarriers in ailments like cancer, Alzheimer’s disease and many other disorders.